SYNERGISTIC EFFECT OF SUBTOXIC-DOSE CISPLATIN AND TRAIL TO MEDIATE APOPTOSIS BY DOWN-REGULATING DECOY RECEPTOR 2 AND UP-REGULATING CASPASE-8, CASPASE-9 AND BAX EXPRESSION ON NCI-H460 AND A549 CELLS

Objective(s): Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell lung cancer (NSCLC) exhibit TRAIL-resistance.The purpose of this study was to determine whether subtoxic-dose cisplatin and TRAIL could synergistically enhance Carr

The High-Altitude Platform Station (HAPS) is an integral component in Non-Terrestrial Network (NTN) which is potential 6G technology.The HAPS as IMT Base Stations (HIBS) in the mobile service is an emerging and promising approach to achieve vertical heterogeneous network.Therefore, some efforts have RE30 been made in order to harmonize the worldwid

Summary: IRF5 polymorphisms are associated with multiple immune-mediated diseases, including ulcerative colitis.IRF5 contributions are attributed to its role in myeloid lineages.How T cell-intrinsic IRF5 contributes to inflammatory outcomes is not well understood.We identify a previously undefined key role for T cell-intrinsic IRF5.In mice, IRF5 in

We consider classical dynamics of a one-dimensional system of N particles bouncing on an oscillating mirror in the presence of gravitational SEASONAL field.The particles behave like hard balls and they are resonantly driven by the mirror.We identify the manifolds the particles move on and derive the effective secular Hamiltonian for resonant motion